• Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort 

      Botteri, Edoardo; Ferrari, Pietro; Roswall, Nina; Tjønneland, Anne; Hjartåker, Anette; Huerta, José María; Fortner, Renée Turzanski; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Pala, Valeria; Pérez-Cornago, Aurora; Sonestedt, Emily; Liedberg, Fredrik; Overvad, Kim; Sánchez, María-José; Gram, Inger Torhild; Stepien, Magdalena; Trijsburg, Laura; Ljungberg, Börje; Johansson, Mikael B.; Kühn, Tilman; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-31)
      Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35-70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 ...
    • Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort 

      van Roekel, Eline H.; Trijsburg, Laura; Assi, Nada; Carayol, Marion; Achaintre, David; Murphy, Neil; Rinaldi, Sabina; Schmidt, Julie A.; Stepien, Magdalena; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salavatore; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Ardanaz, Eva; Lujan-Barroso, Leila; Quirós, José Ramón; Huerta, José María; Molina-Portillo, Elena; Dorronsoro, Miren; Tsilidis, Konstantinos K.; Riboli, Elio; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Håkansson, Anders; Malm, Johan; Weijenberg, Matty P.; Gunter, Marc J.; Jenab, Mazda; Johansson, Mattias; Travis, Ruth C.; Scalbert, Augustin; Ferrari, Pietro (Journal article; Peer reviewed, 2018-05-22)
      Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at ...
    • Novel Biomarkers of Habitual Alcohol Intake and Associations With Risk of Pancreatic and Liver Cancers and Liver Disease Mortality 

      Loftfield, Erikka; Stepien, Magdalena; Viallon, Vivian; Trijsburg, Laura; Rothwell, Joseph A.; Robinot, Nivonirina; Biessy, Carine; Bergdahl, Ingvar A.; Bodén, Stina; Schulze, Matthias B.; Bergman, Manuela; Weiderpass, Elisabete; Schmidt, Julie A.; Zamora-Ros, Raúl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Sonestedt, Emily; Ohlsson, Bodil; Katzke, Verena; Kaaks, Rudolf; Ricceri, Fulvio; Tjønneland, Anne; Dahm, Christina C.; Sánchez, Maria-Jose; Trichopoulou, Antonia; Tumino, Rosario; Chirlaque, María-Dolores; Masala, Giovanna; Ardanaz, Eva; Vermeulen, Roel; Brennan, P; Albanes, Demetrius; Weinstein, Stephanie J.; Scalbert, Augustin; Freedman, Neal D.; Gunter, Marc; Jenab, Mazda; Sinha, Rashmi; Keski-Rahkonen, Pekka; Ferrari, Pietro (Preprint; Manuskript, 2021-05-19)
      Background - Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed because of measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.<p> <p>Methods - Untargeted metabolomics was used to identify metabolites correlated with ...